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ANXA1 and USP7
Number of citations of the paper that reports this interaction (PubMedID
25695607
)
11
Data Source:
BioGRID
(pull down)
ANXA1
USP7
Description
annexin A1
ubiquitin specific peptidase 7
Image
GO Annotations
Cellular Component
Cornified Envelope
Phagocytic Cup
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Cytosol
Actin Filament
Plasma Membrane
Adherens Junction
Focal Adhesion
Cell Surface
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
Extrinsic Component Of Membrane
Cytoplasmic Vesicle Membrane
Extrinsic Component Of External Side Of Plasma Membrane
Extrinsic Component Of Endosome Membrane
Motile Cilium
Early Endosome Membrane
Mitochondrial Membrane
Vesicle
Protein-containing Complex
Sarcolemma
Mast Cell Granule
Collagen-containing Extracellular Matrix
Extracellular Exosome
Synaptic Membrane
Nucleus
Nucleoplasm
Chromosome
Cytosol
Nuclear Body
PML Body
Protein-containing Complex
Molecular Function
Single-stranded DNA Binding
Single-stranded RNA Binding
Signaling Receptor Binding
Calcium Ion Binding
Protein Binding
Phospholipid Binding
Calcium-dependent Phospholipid Binding
Phospholipase A2 Inhibitor Activity
Double-stranded DNA-dependent ATP-dependent DNA Helicase Activity
Identical Protein Binding
Calcium-dependent Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
DNA/DNA Annealing Activity
P53 Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Protein C-terminus Binding
Transcription Factor Binding
Ubiquitin Protein Ligase Binding
Thiol-dependent Ubiquitinyl Hydrolase Activity
Ubiquitinyl Hydrolase Activity
Lys48-specific Deubiquitinase Activity
Biological Process
Neutrophil Homeostasis
Adaptive Immune Response
Monocyte Chemotaxis
Regulation Of Leukocyte Migration
Phagocytosis
Inflammatory Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Cell Shape
Response To X-ray
Myoblast Migration Involved In Skeletal Muscle Regeneration
Peptide Cross-linking
Cytokine-mediated Signaling Pathway
Insulin Secretion
Keratinocyte Differentiation
Prostate Gland Development
Endocrine Pancreas Development
Positive Regulation Of Vesicle Fusion
Positive Regulation Of Prostaglandin Biosynthetic Process
Actin Cytoskeleton Reorganization
Response To Estradiol
DNA Duplex Unwinding
Regulation Of Interleukin-1 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Neutrophil Apoptotic Process
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Gliogenesis
Positive Regulation Of T Cell Proliferation
Regulation Of Cell Proliferation
Response To Drug
Negative Regulation Of Apoptotic Process
Response To Peptide Hormone
Estrous Cycle
Innate Immune Response
Positive Regulation Of T-helper 1 Cell Differentiation
Negative Regulation Of T-helper 2 Cell Differentiation
Negative Regulation Of Exocytosis
Alpha-beta T Cell Differentiation
Regulation Of Hormone Secretion
Arachidonic Acid Secretion
Regulation Of Inflammatory Response
Cellular Response To Hydrogen Peroxide
Hepatocyte Differentiation
Prolactin Secretion
Response To Interleukin-1
Cellular Response To Glucocorticoid Stimulus
Granulocyte Chemotaxis
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Wound Healing
Neutrophil Clearance
Cell-cell Adhesion
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Phospholipase A2 Activity
Negative Regulation Of Interleukin-8 Secretion
Regulation Of Gluconeogenesis
Transcription-coupled Nucleotide-excision Repair
Ubiquitin-dependent Protein Catabolic Process
Multicellular Organism Development
Maintenance Of DNA Methylation
Viral Process
Protein Ubiquitination
Protein Deubiquitination
Regulation Of Protein Stability
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Monoubiquitinated Protein Deubiquitination
Histone H2B Conserved C-terminal Lysine Deubiquitination
Regulation Of Circadian Rhythm
Rhythmic Process
Protein Stabilization
Regulation Of DNA-binding Transcription Factor Activity
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Positive Regulation Of DNA Demethylation
Regulation Of Telomere Capping
Pathways
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands
Smooth Muscle Contraction
Interleukin-4 and Interleukin-13 signaling
Ub-specific processing proteases
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Regulation of TP53 Degradation
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Regulation of PTEN localization
Drugs
Amcinonide
Hydrocortisone
Dexamethasone
Diseases
GWAS
Blood protein levels (
28240269
)
Chronotype (
30696823
)
Metabolite levels (
23823483
)
Parkinson's disease (
26227905
)
Schizophrenia, bipolar disorder and depression (combined) (
20713499
)
Urate levels in obese individuals (
25811787
)
Chronotype (
30696823
)
Platelet count (
27863252
)
Platelet distribution width (
27863252
)
Interacting Genes
33 interacting genes:
APBB1
CCT7
COPS6
CSAD
CZIB
DYSF
EGFR
ERG28
FAF1
FPR1
GAPDH
HMGA1
HSPB1
KLHL23
KMT2B
KRT8
LRIF1
MEIS2
OTUB1
PRKCI
RPA1
S100A11
SRC
SUMO2
TGM2
TRPM7
UBE2D1
UBE2I
UBE3A
UCHL5
UNC119
USP7
YWHAQ
99 interacting genes:
ABRAXAS2
ACD
ANXA1
ARNT2
ATXN1
BCOR
BEND5
CBX8
CHEK1
CLSPN
CREB3L3
CRY1
CSNK2A1
CTNNB1
DAXX
DNAJA3
DNMT3A
EWSR1
EZH2
FOXN2
GATA1
H2AC20
H2BU1
HECW1
HERPUD1
HIF1A
HTRA2
HUWE1
IFNAR1
KAT5
KDM1A
KLHL8
MAGEE1
MAL
MARCHF7
MCMBP
MDM2
MDM4
MYC
MYD88
NECAB2
NOTCH1
OTUD4
PCGF2
PEG3
PEPD
PHF8
PHLDB2
PICK1
PLA2G2A
PLEKHO1
POLH
PPARG
PPL
PTEN
RAD18
RADIL
RARA
RB1
RBCK1
RELA
RFFL
RNF168
RNF220
SCML2
SIRT7
SMAD3
SNCA
SUMO2
SYVN1
TANK
TBCB
TFIP11
TMPO
TP53
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
TRIM22
TRIM31
TRIM54
TRIM55
TRIM63
TRIM8
TRO
UBA52
UBC
UBE2D3
UBE2E1
UBE2S
USP21
USP28
WWP2
XPC
ZMYND8
ZNF423
Entrez ID
301
7874
HPRD ID
01060
03950
Ensembl ID
ENSG00000135046
ENSG00000187555
Uniprot IDs
P04083
Q5TZZ9
B7Z855
B7ZAX6
Q6U8A4
Q93009
PDB IDs
1AIN
1BO9
1QLS
5VFW
1NB8
1NBF
1YY6
1YZE
2F1W
2F1X
2F1Y
2F1Z
2FOJ
2FOO
2FOP
2KVR
2XXN
2YLM
3MQR
3MQS
4JJQ
4KG9
4M5W
4M5X
4PYZ
4WPH
4WPI
4YOC
4YSI
4Z96
4Z97
5C56
5C6D
5FWI
5GG4
5J7T
5JTJ
5JTV
5KYB
5KYC
5KYD
5KYE
5KYF
5N9R
5N9T
5NGE
5NGF
5UQV
5UQX
5VS6
5VSB
5VSK
5WHC
6F5H
Enriched GO Terms of Interacting Partners
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