GZMM and DFFA

Number of citations of the paper that reports this interaction (PubMedID 16818775)
12

Data Source:
BioGRID (enzymatic study)

		GZMM	DFFA
Description		granzyme M	DNA fragmentation factor subunit alpha
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GO Annotations	Cellular Component	Extracellular Region Membrane	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity	Protein Binding Protein Domain Specific Binding Protein Binding Involved In Protein Folding Deoxyribonuclease Inhibitor Activity
	Biological Process	T Cell Mediated Cytotoxicity Proteolysis Apoptotic Process Cell Death Cytolysis Innate Immune Response	Apoptotic DNA Fragmentation Negative Regulation Of Deoxyribonuclease Activity Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Chaperone-mediated Protein Folding Thymocyte Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Apoptotic DNA Fragmentation
Pathways		Alternative complement activation	Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488)	Depression in smokers ( 30219690) Male-pattern baldness ( 29146897 28196072)
Interacting Genes		5 interacting genes: DFFA EZR NPM1 PARP1 TUBA1B	11 interacting genes: CASP3 CASP7 CIDEB DFFB EWSR1 GZMB GZMM NECAB2 STRN4 YWHAG YWHAZ
Entrez ID		3004	1676
HPRD ID		02633	03531
Ensembl ID		ENSG00000197540	ENSG00000160049
Uniprot IDs		P51124	A0A024R4H5 O00273
PDB IDs		1LZP 2ZGC 2ZGH 2ZGJ 2ZKS	1IBX 1IYR 1KOY
Enriched GO Terms of Interacting Partners?
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