UBQLN1 and PNMA1

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		UBQLN1	PNMA1
Description		ubiquilin 1	PNMA family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleoplasm Cytoplasm Autophagosome Endoplasmic Reticulum Cytosol Plasma Membrane Aggresome Cytoplasmic Vesicle Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleolus Cytoplasm
	Molecular Function	Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Autophagosome Assembly Ubiquitin-dependent Protein Catabolic Process Macroautophagy Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Response To Endoplasmic Reticulum Stress Aggrephagy Cellular Response To Hypoxia Autophagosome Maturation Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process
Pathways		Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		164 interacting genes: ABCC2 ACOT7 ADRM1 AGPAT5 AGR2 AGR3 APP ASCL1 ATXN3 BPIFA1 C1QA C1QTNF2 CALU CCL7 CD47 CD99 CD99L2 CHGB CHRNA3 CHRNA4 CHRNB4 CLCN2 COL10A1 COL1A2 COLGALT2 COMTD1 COPS4 CSTF2 CSTF2T CTAG1B CTAG2 CYB5R1 DEFA6 DNAJB2 DOLK EFEMP2 EP300 EPS15 ERP27 ETNK1 F8 FAM189A2 FAM86B3P FAS FBXO25 FCGR2A FGF7 FKBP2 FN1 FZD7 GABRA1 GABRA2 GABRA3 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GHRL GIT2 GKAP1 GPX3 GRM2 GYPB HERC3 HES1 HGS HK2 HSD17B12 HSPA13 IGL IGLC1 IGLV2-14 IL6ST IST1 ITPRIPL1 KLHL42 LHX4 LITAF MANBAL MAP3K1 MCM7 MIEF1 MIEF2 MLLT6 MTNR1A MTOR NAXD NBL1 NDE1 NEDD8 NGLY1 NLGN3 NME3 NPPA NPY NT5C3A NUP58 P4HB PARVA PBXIP1 PIK3IP1 PLAAT3 PNMA1 PPIB PPIC PRAP1 PRB1 PRPF40A PSEN1 PSEN2 PSMD4 PSMD6 PTN RARA RASSF5 RIC8A RNF208 RPN1 RSRC2 RTL8A RTL8B RTL8C SCG2 SCG5 SCMH1 SERPINE1 SERPINI2 SIL1 SLC29A2 SMAD9 SMIM2 SMR3B SMURF1 SPARC SRGN STMN3 SYNJ2BP TARDBP TFF1 TICAM1 TLR4 TMCO6 TMEM31 TMEM37 TMEM67 TMUB2 TNFRSF1A TNFRSF1B TREX1 TRIM32 TXNDC12 UBB UBC UBE2V1 UBE3A UBQLN4 UBXN1 WBP2 XPO4 ZFAND2B ZG16 ZG16B ZNF343	131 interacting genes: ABHD17A ANKRD36BP1 APTX ARID5A ASMTL ATP5PO ATXN7 BEX2 BYSL C21orf58 C8orf33 CARHSP1 CCDC146 CCDC198 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CHIC2 CHMP2B CNNM3 COX5B DAXX DCTN4 EAF2 EHHADH ENKD1 FAM107A FAM110A FBF1 FBXL18 FEM1C FMNL2 GATA1 GEM GPANK1 GPR25 GRAP2 GTPBP10 HDAC4 HGS HNRNPLL HOXB9 INO80B IVD KANSL1 KAT2B LENG1 LIN37 LMO3 LNX1 LSM2 MAB21L2 MACIR MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 NIF3L1 NPBWR2 NTAQ1 NUDT16L1 PARD3 PARD6B PCGF6 PIN1 PIN4 PNMA5 PNMA6A POLDIP3 POLL POLM PRKAB2 PRKCG PRKCI PRPF31 PSMA1 RAPGEF3 RBM41 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 SSX2IP STAMBPL1 SUV39H2 TCEANC TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRPV6 TSPYL4 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 WDR25 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF410 ZNF564 ZNF581 ZNF688
Entrez ID		29979	9240
HPRD ID		05440	04926
Ensembl ID		ENSG00000135018	ENSG00000176903
Uniprot IDs		A0A024R258 Q9UMX0	Q8ND90
PDB IDs		2JY5 2JY6 2KLC
Enriched GO Terms of Interacting Partners?
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