HSPA13 and POLE4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		HSPA13	POLE4
Description		heat shock protein family A (Hsp70) member 13	DNA polymerase epsilon 4, accessory subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex
	Molecular Function	Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Response To Unfolded Protein Vesicle-mediated Transport Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding	G1/S Transition Of Mitotic Cell Cycle DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication DNA Biosynthetic Process
Pathways		Regulation of HSF1-mediated heat shock response	Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs		Copper	Cladribine
Diseases
GWAS
Interacting Genes		8 interacting genes: BAG6 POLE4 RMI1 SGTA SSR1 UBQLN1 UBQLN2 UBQLN4	6 interacting genes: HSPA13 NFYB POLE POLE2 POLE3 UBE3A
Entrez ID		6782	56655
HPRD ID		03061	16238
Ensembl ID		ENSG00000155304	ENSG00000115350
Uniprot IDs		A0A140VK72 P48723	Q9NR33
PDB IDs
Enriched GO Terms of Interacting Partners?
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