GYPA and SGTA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		GYPA	SGTA
Description		glycophorin A (MNS blood group)	small glutamine rich tetratricopeptide repeat containing alpha
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane Integral Component Of Membrane	Nucleus Cytoplasm Cytosol Membrane TRC Complex Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding Protein Self-association Molecular Adaptor Activity BAT3 Complex Binding
	Biological Process	Viral Entry Into Host Cell Leukocyte Migration	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Viral Process Ubiquitin-dependent ERAD Pathway Chaperone-mediated Protein Folding Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Chaperone-mediated Protein Folding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways		Cell surface interactions at the vascular wall	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Bipolar disorder (body mass index interaction) ( 24322204) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease ( 30804561 25101718) Diastolic blood pressure ( 27841878) Femoral neck bone mineral density ( 30172743) Height ( 31562340) Lung function (low FEV1 vs high FEV1) ( 26423011) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Monocyte count ( 27863252) Platelet count ( 27863252) Plateletcrit ( 27863252) Red blood cell count ( 29403010) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Severe malaria ( 26416757) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: CREB3 KEAP1 SGTA	98 interacting genes: ADIPOQ ADRM1 AGR3 BAG6 BCL2L12 BTC C1QA C1QTNF1 C1QTNF6 C3orf52 CD79B CD99 CD99L2 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA4 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KASH5 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NAXD NME3 NR3C1 NXF1 PBXIP1 PCDHA4 PFN2 PGR PIAS1 PLAAT4 PPIB PPIC PPP1R3C PRAP1 PTN RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B
Entrez ID		2993	6449
HPRD ID		07508	04568
Ensembl ID		ENSG00000170180	ENSG00000104969
Uniprot IDs		A0A0C4DFT7 A0A2R8Y7F9 E9PD10 P02724 Q14419	O43765
PDB IDs		1AFO 1MSR 2KPE 2KPF 5EH4 5EH6	2VYI 4CPG 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?
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