HOOK2 and VPS41

Number of citations of the paper that reports this interaction (PubMedID 18799622)
41

Data Source:
HPRD (in vivo)

		HOOK2	VPS41
Description		hook microtubule tethering protein 2	VPS41 subunit of HOPS complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex Intracellular Membrane-bounded Organelle FHF Complex	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding
	Biological Process	Endocytosis Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport	Protein Targeting To Vacuole Autophagy Endosome To Lysosome Transport Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Vacuole Fusion, Non-autophagic Regulated Exocytosis Late Endosome To Lysosome Transport
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Monocyte count ( 27863252)	Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)
Interacting Genes		41 interacting genes: ABLIM1 AKTIP ANKRD11 ANKRD36BP1 AP1M1 APEX2 CCDC33 CWF19L2 DUSP13 EPS8 FAM107A HAUS1 HOOK1 HOOK3 IQCE ITSN2 KANSL1 KAT7 KIAA0408 KLK15 MCM10 PIMREG PSMF1 RALBP1 RIBC2 RITA1 RNF6 SMARCB1 SUV39H1 TPM3 TRMT1 USP2 UTP14A UTP14C VPS16 VPS41 ZBTB47 ZC2HC1C ZC3H14 ZNF250 ZNF638	12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B
Entrez ID		29911	27072
HPRD ID		09698	10402
Ensembl ID		ENSG00000095066	ENSG00000006715
Uniprot IDs		Q96ED9	P49754
PDB IDs
Enriched GO Terms of Interacting Partners?
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