GTF2A1 and GTF2E2

Number of citations of the paper that reports this interaction (PubMedID 9618479)
14

Data Source:
BioGRID (pull down, pull down)
HPRD (in vitro)

		GTF2A1	GTF2E2
Description		general transcription factor IIA subunit 1	general transcription factor IIE subunit 2
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Cytosol	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Nuclear Speck
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity	DNA Binding RNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II Positive Regulation Of Nucleic Acid-templated Transcription	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance Estrogen-dependent gene expression	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917)	Cognitive performance ( 20125193) Metabolite levels (X-11787) ( 23934736)
Interacting Genes		18 interacting genes: BCL3 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4	23 interacting genes: APP ATF7IP CCNH CDK7 ERCC3 ERCC6 FOS GTF2A1 GTF2B GTF2E1 GTF2F1 GTF2F2 GTF2H1 JUN KLF5 MCC MDM2 MNAT1 NUP62 SND1 SUPT16H TBP XPA
Entrez ID		2957	2961
HPRD ID		02748	01800
Ensembl ID		ENSG00000165417	ENSG00000197265
Uniprot IDs		P52655	P29084
PDB IDs		1NVP 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5M4S 6MZM 6O9L	1D8J 1D8K 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L
Enriched GO Terms of Interacting Partners?
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