GRM2 and GRIP1

Number of citations of the paper that reports this interaction (PubMedID 11891216)
43

Data Source:
BioGRID (pull down)

		GRM2	GRIP1
Description		glutamate metabotropic receptor 2	glutamate receptor interacting protein 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Axon Dendrite Presynaptic Membrane Integral Component Of Postsynaptic Membrane	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Group II Metabotropic Glutamate Receptor Activity G Protein-coupled Receptor Activity Calcium Channel Regulator Activity Protein Binding Glutamate Receptor Activity	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Receptor Signaling Complex Scaffold Activity Glucocorticoid Receptor Binding Androgen Receptor Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Glutamate Secretion Regulation Of Synaptic Transmission, Glutamatergic Glutamate Homeostasis	Positive Regulation Of Signal Transduction Dendrite Development Androgen Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Transcription, DNA-templated Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)	Trafficking of GluR2-containing AMPA receptors
Drugs		LY2140023
Diseases
GWAS			Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		9 interacting genes: GNA15 GNAQ GRIP1 LMNA NAALADL2 RGS12 SDCBP TAMALIN UBQLN1	35 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EFNA5 EFNB1 EFNB2 EP300 ESR1 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 IRF3 NCOA6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR
Entrez ID		2912	23426
HPRD ID		04977	19086
Ensembl ID		ENSG00000164082	ENSG00000155974
Uniprot IDs		Q14416	Q9Y3R0
PDB IDs		4XAQ 4XAS 5CNI 5CNJ 5KZN 5KZQ	2JIL
Enriched GO Terms of Interacting Partners?
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