GRIP1 and GRM3

Number of citations of the paper that reports this interaction (PubMedID 11891216)
43

Data Source:
BioGRID (two hybrid, pull down)

		GRIP1	GRM3
Description		glutamate receptor interacting protein 1	glutamate metabotropic receptor 3
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Axon Dendritic Spine Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Receptor Signaling Complex Scaffold Activity Glucocorticoid Receptor Binding Androgen Receptor Binding	Group II Metabotropic Glutamate Receptor Activity G Protein-coupled Receptor Activity Calcium Channel Regulator Activity Glutamate Receptor Activity
	Biological Process	Positive Regulation Of Signal Transduction Dendrite Development Androgen Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Transcription, DNA-templated Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Regulation Of Synaptic Transmission, Glutamatergic
Pathways		Trafficking of GluR2-containing AMPA receptors	G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs			LY2140023
Diseases
GWAS		Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 27611488) Autism spectrum disorder or schizophrenia ( 28540026) Brachial circumference ( 22479309) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling worry ( 29500382) Neurociticism ( 29500382) Neuroticism ( 29255261) Schizophrenia ( 28991256 25056061 29483656 30285260) Seborrheic dermatitis ( 29203360) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		35 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EFNA5 EFNB1 EFNB2 EP300 ESR1 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 IRF3 NCOA6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR	6 interacting genes: CALM1 GRIP1 PICK1 PPM1A SDCBP TAMALIN
Entrez ID		23426	2913
HPRD ID		19086	03070
Ensembl ID		ENSG00000155974	ENSG00000198822
Uniprot IDs		Q9Y3R0	A4D1D0 Q14832
PDB IDs		2JIL	1S8M 3SM9 4XAR 5CNK 5CNM 6B7H
Enriched GO Terms of Interacting Partners?
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