FHOD1 and LNPEP

Number of citations of the paper that reports this interaction (PubMedID 12677009)
10

Data Source:
HPRD (in vitro, two hybrid)

		FHOD1	LNPEP
Description		formin homology 2 domain containing 1	leucyl and cystinyl aminopeptidase
Image
GO Annotations	Cellular Component	Stress Fiber Cell Nucleus Nucleoplasm Cytoplasm Cytosol Intercalated Disc Membrane Bleb	Extracellular Region Cytoplasm Lysosomal Membrane Cytosol Integral Component Of Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Early Endosome Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity
	Biological Process	Nuclear Migration Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Stress Fiber Assembly Positive Regulation Of Stress Fiber Assembly Establishment Of Centrosome Localization	Protein Polyubiquitination Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Cell-cell Signaling Female Pregnancy Protein Catabolic Process Peptide Catabolic Process SMAD Protein Signal Transduction Negative Regulation Of Cold-induced Thermogenesis
Pathways			Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
Interacting Genes		21 interacting genes: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 NLGN3 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 YWHAZ ZMYND8	8 interacting genes: FATE1 FHOD1 REL SLC2A4 SMAD9 TCF4 TNKS TNKS2
Entrez ID		29109	4012
HPRD ID		06049	01041
Ensembl ID		ENSG00000135723	ENSG00000113441
Uniprot IDs		A0A068F7M9 Q9Y613	Q9UIQ6
PDB IDs		3DAD	4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6
Enriched GO Terms of Interacting Partners?
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