UBE2T and FANCL

Number of citations of the paper that reports this interaction (PubMedID 30335751)
2

Data Source:
BioGRID (pull down)

		UBE2T	FANCL
Description		ubiquitin conjugating enzyme E2 T	FA complementation group L
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Nuclear Body Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein K29-linked Ubiquitination Interstrand Cross-link Repair Protein K27-linked Ubiquitination Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Interstrand Cross-link Repair Regulation Of Cell Proliferation
Pathways		Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes	Fanconi Anemia Pathway
Drugs
Diseases			Fanconi anemia
GWAS		Breast cancer ( 23535733) Celiac disease ( 23936387)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 31453325 20935630) Body mass index variance ( 31453325) Childhood absence epilepsy ( 30531953) Chronotype ( 30696823) Epilepsy ( 25087078 30531953) Feeling miserable ( 29500382) Generalized epilepsy ( 30531953) Hirschsprung disease ( 27702942) Initial pursuit acceleration ( 29064472) Irritable mood ( 29500382) Obesity ( 23563607) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Schizophrenia ( 25056061 29483656) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077) Type 2 diabetes ( 30718926) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		22 interacting genes: AMFR ARIH2 BRCA1 CDK2 CHEK1 FANCD2 FANCL LNX2 MARCHF5 MGRN1 PCGF2 PRKCG PRKN RNF128 RNF144B RNF31 RNF4 ROCK1 RPS6KA1 TRIM27 UBA1 UBA6	26 interacting genes: ACVR1 BMPR1B CHCHD3 CTBP1 DOCK8 EIF4ENIF1 FAAP100 FANCB FANCD2 FANCF FANCI GGN GRN HES1 IHO1 IKZF3 KIFC3 LZTS2 PCNA RBM45 RIMBP3 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W
Entrez ID		29089	55120
HPRD ID		13704	06997
Ensembl ID		ENSG00000077152	ENSG00000115392
Uniprot IDs		A0A024R9A9 Q9NPD8	Q9NW38
PDB IDs		1YH2 4CCG 5NGZ 5OJJ 6R75	3ZQS 4CCG
Enriched GO Terms of Interacting Partners?
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