FANCL and FANCB

Number of citations of the paper that reports this interaction (PubMedID 16720839)
42

Data Source:
BioGRID (affinity chromatography technology, two hybrid, two hybrid)

		FANCL	FANCB
Description		FA complementation group L	FA complementation group B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Nuclear Body Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex	Nucleoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Interstrand Cross-link Repair Regulation Of Cell Proliferation	Interstrand Cross-link Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		Fanconi Anemia Pathway	Fanconi Anemia Pathway
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 31453325 20935630) Body mass index variance ( 31453325) Childhood absence epilepsy ( 30531953) Chronotype ( 30696823) Epilepsy ( 25087078 30531953) Feeling miserable ( 29500382) Generalized epilepsy ( 30531953) Hirschsprung disease ( 27702942) Initial pursuit acceleration ( 29064472) Irritable mood ( 29500382) Obesity ( 23563607) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Schizophrenia ( 25056061 29483656) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077) Type 2 diabetes ( 30718926) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		26 interacting genes: ACVR1 BMPR1B CHCHD3 CTBP1 DOCK8 EIF4ENIF1 FAAP100 FANCB FANCD2 FANCF FANCI GGN GRN HES1 IHO1 IKZF3 KIFC3 LZTS2 PCNA RBM45 RIMBP3 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W	4 interacting genes: F3 FAAP100 FANCF FANCL
Entrez ID		55120	2187
HPRD ID		06997	06557
Ensembl ID		ENSG00000115392	ENSG00000181544
Uniprot IDs		Q9NW38	A0A024RBW1 Q8NB91
PDB IDs		3ZQS 4CCG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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