NDUFAF4 and NDUFAF3

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		NDUFAF4	NDUFAF3
Description		NADH:ubiquinone oxidoreductase complex assembly factor 4	NADH:ubiquinone oxidoreductase complex assembly factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Membrane	Nucleus Mitochondrial Inner Membrane
	Molecular Function	Protein Binding Calmodulin Binding	Protein Binding
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly	Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Complex I biogenesis	Complex I biogenesis
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome	Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mood instability ( 31168069) Ulcerative colitis ( 28067908)
Interacting Genes		1 interacting genes: NDUFAF3	8 interacting genes: GEM KRTAP10-3 LSM1 NDUFAF4 RBCK1 REL SCAP SNRPA
Entrez ID		29078	25915
HPRD ID		10795	16809
Ensembl ID		ENSG00000123545	ENSG00000178057
Uniprot IDs		Q9P032	A4FU71 Q9BU61 Q9Y3Z0
PDB IDs
Enriched GO Terms of Interacting Partners?
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