GRIK5 and GOLM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		GRIK5	GOLM1
Description		glutamate ionotropic receptor kainate type subunit 5	golgi membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Nucleoplasm Endoplasmic Reticulum Plasma Membrane Cell Junction Dendrite Kainate Selective Glutamate Receptor Complex Presynaptic Membrane Terminal Bouton Perikaryon Postsynaptic Membrane Hippocampal Mossy Fiber To CA3 Synapse Postsynaptic Density Membrane Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Plasma Membrane
	Molecular Function	Glutamate Receptor Activity Ligand-gated Ion Channel Activity Kainate Selective Glutamate Receptor Activity SH3 Domain Binding PDZ Domain Binding Signaling Receptor Activity Identical Protein Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Protein Binding
	Biological Process	Protein Retention In ER Lumen Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Receptor Clustering Positive Regulation Of Neuron Apoptotic Process Modulation Of Chemical Synaptic Transmission Establishment Of Localization In Cell Excitatory Postsynaptic Potential Cellular Response To Glucose Stimulus	Nucleus Organization Regulation Of Lipid Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Activation of Ca-permeable Kainate Receptor	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Glutamic Acid
Diseases
GWAS		Bipolar disorder ( 21771265)	Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		8 interacting genes: DLG4 GOLM1 GPAA1 GRID2 GRIK2 GRIK3 LRSAM1 MLF1	27 interacting genes: B3GNT4 C1orf174 CIAO1 CLK1 DCK DCTN2 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 GEMIN7 GRIK5 KCNE3 LSM12 MED22 NIPSNAP3A NRSN2 RACK1 RPA2 RPL13A SLC40A1 SYT1 TLE1 ZFAND3
Entrez ID		2901	51280
HPRD ID		02614	08428
Ensembl ID		ENSG00000105737	ENSG00000135052
Uniprot IDs		Q16478	B3KNK9 Q8NBJ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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