NSMCE2 and TXLNA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NSMCE2	TXLNA
Description		NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase	taxilin alpha
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm Nuclear Body PML Body Smc5-Smc6 Complex	Extracellular Region Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Zinc Ion Binding SUMO Transferase Activity	Protein Binding Syntaxin Binding
	Biological Process	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination Double-strand Break Repair Via Nonhomologous End Joining Cell Cycle Protein Sumoylation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Positive Regulation Of Mitotic Metaphase/anaphase Transition Cell Division Cellular Senescence	Exocytosis Cytokine-mediated Signaling Pathway B Cell Activation
Pathways		SUMOylation of DNA damage response and repair proteins	Other interleukin signaling
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 24931836) Amyotrophic lateral sclerosis or frontotemporal dementia ( 24931836) C-reactive protein levels ( 30388399) Diffusing capacity of carbon monoxide ( 30694715) Pursuit maintenance gain ( 29064472) Response to statin therapy ( 20339536)
Interacting Genes		4 interacting genes: ETV1 TSNAX TXLNA USP28	52 interacting genes: AZI2 BRCA1 BTF3 BTF3L4 CBY2 CCDC136 CCHCR1 CDR2 CEP44 CEP57L1 CEP63 DEUP1 DTNB EIF4ENIF1 GOLGA2 GORASP2 HAUS3 HYPK IKBKG KANK2 KRT13 KRT15 KRT20 KRT31 KRT38 KRT40 LCA5 MBIP MED4 MEOX1 MEOX2 NACA NDC80 NMI NSMCE2 NUP62 PPFIA1 RCOR3 RINT1 SMARCE1 STMN2 STX1A STX3 STX4 TCL1A TFIP11 TNIP1 TP53BP2 TXLNB USHBP1 VPS52 WASHC3
Entrez ID		286053	200081
HPRD ID		08131	09408
Ensembl ID		ENSG00000156831	ENSG00000084652
Uniprot IDs		A0A024R9J6 E5RFJ1 Q96MF7	P40222
PDB IDs		2YU4
Enriched GO Terms of Interacting Partners?
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