ANK1 and EPB42

Number of citations of the paper that reports this interaction (PubMedID 2968981)
24

Data Source:
HPRD (in vitro)

		ANK1	EPB42
Description		ankyrin 1	erythrocyte membrane protein band 4.2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Side Of Plasma Membrane Spectrin-associated Cytoskeleton Membrane Basolateral Plasma Membrane Sarcoplasmic Reticulum Z Disc Axolemma M Band Sarcolemma Axon Initial Segment Postsynaptic Membrane	Cytoskeleton Plasma Membrane Cortical Cytoskeleton
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Enzyme Binding Protein Phosphatase Binding Spectrin Binding Ion Channel Binding ATPase Binding	Protein-glutamine Gamma-glutamyltransferase Activity Structural Constituent Of Cytoskeleton Protein Binding ATP Binding
	Biological Process	Exocytosis ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Signal Transduction Positive Regulation Of Organelle Organization Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Plasma Membrane	Cell Morphogenesis Cytoskeleton Organization Regulation Of Cell Shape Peptide Cross-linking Hemoglobin Metabolic Process Erythrocyte Maturation Spleen Development Iron Ion Homeostasis
Pathways		Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport
Drugs
Diseases		Hereditary spherocytosis (SPH)	Hereditary spherocytosis (SPH)
GWAS		Birth weight ( 31043758 27680694) Corrected insulin response ( 24699409) Corrected insulin response adjusted for insulin sensitivity index ( 24699409) Glycated hemoglobin levels ( 24647736 20858683 31213470 28898252) Granulocyte percentage of myeloid white cells ( 27863252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Insulin levels adjusted for BMI ( 24699409) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252 28017375) Mean corpuscular volume ( 27863252) Neutrophil percentage of white cells ( 27863252) Pulmonary function decline ( 22424883) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sleep duration ( 30531941) Type 2 diabetes ( 22885922 24509480 30054458 29358691 30297969 26818947 30718926 28869590 22456796)
Interacting Genes		19 interacting genes: BLOC1S6 CD44 EPB42 HSPB1 ITPR3 KCTD6 L1CAM NBPF3 NFASC OBSCN RHAG RYR1 SLC4A1 SLC4A3 SPTA1 SPTAN1 SPTB TIAM1 TTN	13 interacting genes: ANK1 ANK2 BLOC1S4 CD47 DMTN EPB41 KRAS MAPK14 SLC4A1 SLC4A2 SPINK7 SPTAN1 STX12
Entrez ID		286	2038
HPRD ID		01693	01517
Ensembl ID		ENSG00000029534	ENSG00000166947
Uniprot IDs		B3KX39 P16157	P16452
PDB IDs		1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
Enriched GO Terms of Interacting Partners?
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