GLP1R and CD63

Number of citations of the paper that reports this interaction (PubMedID 28597972)
0

Data Source:
BioGRID (protein complementation assay)

		GLP1R	CD63
Description		glucagon like peptide 1 receptor	CD63 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Extracellular Space Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endosome Membrane Platelet Dense Granule Membrane Intrinsic Component Of Plasma Membrane Late Endosome Membrane Endosome Lumen Multivesicular Body Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome Multivesicular Body, Internal Vesicle
	Molecular Function	Transmembrane Signaling Receptor Activity Glucagon Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Glucagon-like Peptide 1 Receptor Activity	Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Learning Or Memory Regulation Of Heart Contraction CAMP-mediated Signaling Positive Regulation Of Blood Pressure Regulation Of Insulin Secretion Cellular Response To Glucagon Stimulus Response To Psychosocial Stress	Positive Regulation Of Receptor Internalization Platelet Degranulation Cell-matrix Adhesion Protein Transport Cell Migration Cellular Protein Localization Endosome To Melanosome Transport Neutrophil Degranulation Pigment Granule Maturation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production	Platelet degranulation Neutrophil degranulation
Drugs		Glucagon recombinant Exenatide Liraglutide Albiglutide Dulaglutide Lixisenatide Semaglutide
Diseases
GWAS		Blood sugar levels ( 29403010) Fasting blood glucose ( 25631608) Fasting blood glucose adjusted for BMI ( 25625282)	Advanced age-related macular degeneration ( 26691988) Cardiac Troponin-T levels ( 31014085)
Interacting Genes		106 interacting genes: ACSF3 AGXT AIG1 APH1A ARFRP1 ASGR2 ATP13A1 ATP5MC3 ATP6AP2 C18orf32 C4orf3 CALM1 CAND2 CAV1 CCDC167 CD63 CD81 CELA3B CEND1 CFI CLDN7 CLIP4 CLPS CNIH4 COMT CYSTM1 DAD1 DHRS7 EBP ELOVL1 EMC7 EMP2 ERP29 FGL1 FTL GABBR2 GCG GJB1 GNAS GP2 GPR108 GPR37 GPRASP1 GRINA HAMP HPN IER3 IFITM3 KHK KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 LAPTM4A LINC00269 MFSD5 MRPL22 MT-ATP6 MT-ND4L MTCH2 MYL6 NOTCH2NLA NRGN NUCKS1 OCIAD2 OST4 P4HTM PAM PAQR6 PGRMC1 PIGG POMT2 PPIB PRSS2 PSMD8 RAB5B RAB5C RNF5 RTN3 RTN4 RTRAF SAA1 SCGB2A1 SEC11C SELENOK SERPINA1 SLC15A4 SLC37A4 SPTSSA STMN1 STMN3 STOML2 SVOP SYNGR3 SYNGR4 SYS1 TM4SF4 TMBIM6 TMCO3 TMEM147 TMEM176B TOMM6 TSPAN13 UGT1A9 VAPB ZNF99	14 interacting genes: AP4M1 CD82 CD9 GLP1R HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SRF TIMP1 VKORC1
Entrez ID		2740	967
HPRD ID		00677	01121
Ensembl ID		ENSG00000112164	ENSG00000135404
Uniprot IDs		A0A142FHB8 P43220	A0A024RB05 P08962
PDB IDs		3C59 3C5T 3IOL 4ZGM 5E94 5NX2 5OTT 5OTU 5OTV 5OTW 5OTX 5VEW 5VEX 6B3J 6GB1
Enriched GO Terms of Interacting Partners?
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