CD63 and SDC1

Number of citations of the paper that reports this interaction (PubMedID 22660413)
377

Data Source:
BioGRID (pull down)

		CD63	SDC1
Description		CD63 molecule	syndecan 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endosome Membrane Platelet Dense Granule Membrane Intrinsic Component Of Plasma Membrane Late Endosome Membrane Endosome Lumen Multivesicular Body Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome Multivesicular Body, Internal Vesicle	Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Protein-containing Complex Lysosomal Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Platelet Degranulation Cell-matrix Adhesion Protein Transport Cell Migration Cellular Protein Localization Endosome To Melanosome Transport Neutrophil Degranulation Pigment Granule Maturation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Integrin-mediated Signaling Pathway	Retinoid Metabolic Process Ureteric Bud Development Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Inflammatory Response Cell Migration Cytokine-mediated Signaling Pathway Wound Healing Odontogenesis Response To Hydrogen Peroxide Myoblast Development Leukocyte Migration Response To Glucocorticoid Response To CAMP Response To Calcium Ion Striated Muscle Cell Development Sertoli Cell Development Canonical Wnt Signaling Pathway Positive Regulation Of Exosomal Secretion Positive Regulation Of Extracellular Exosome Assembly
Pathways		Platelet degranulation Neutrophil degranulation	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Syndecan interactions Syndecan interactions Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Other interleukin signaling Retinoid metabolism and transport
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Cardiac Troponin-T levels ( 31014085)	Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Body mass index ( 28892062) Seasonality ( 25562672)
Interacting Genes		14 interacting genes: AP4M1 CD82 CD9 GLP1R HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SRF TIMP1 VKORC1	16 interacting genes: APP CASK CCL5 CD63 CTSG CXCL8 ELANE FGF2 HGF IGFBP7 LACRT MDK MMP14 PTEN PTN SDCBP
Entrez ID		967	6382
HPRD ID		01121	01718
Ensembl ID		ENSG00000135404	ENSG00000115884
Uniprot IDs		A0A024RB05 P08962	P18827
PDB IDs			4GVC 4GVD 6EJE
Enriched GO Terms of Interacting Partners?
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