GLI1 and SUFU

  • Number of citations of the paper that reports this interaction (PubMedID 10559945)
  • 169
  • Data Source:
  • HPRD (in vitro, in vivo)

GLI1

SUFU

Description GLI family zinc finger 1 SUFU negative regulator of hedgehog signaling
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergy ( 27182965)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Creatinine levels ( 29403010)
  • Estimated glomerular filtration rate ( 30604766)
  • Glomerular filtration rate ( 29403010)
  • Height ( 28552196)
  • Nickel levels ( 26025379)
  • Optic disc size ( 31809533)
  • Prostate cancer ( 23535732)
  • Sum eosinophil basophil counts ( 27863252)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • White blood cell count ( 29403010)
Interacting Genes 18 interacting genes: CRYBA4 DYRK1A FEM1B GCC1 IKBKB PRKAA2 PRKACA PRMT5 RAI1 STK36 SUFU TAF9 TRIM42 USP48 WDR77 XBP1 ZIC1 ZIC2 27 interacting genes: BTRC FBXL17 GLI1 GLI2 GLI3 GLIS3 HDX HMGA1 HNRNPA1 ITCH LAMTOR3 LGALS3 MID1IP1 NCOA3 PEX26 PIAS1 QPRT RBPJ RCN3 RNF19A SAP18 SETDB1 STK36 ZNF219 ZNF263 ZNF446 ZNF764
Entrez ID 2735 51684
HPRD ID 01311 06124
Ensembl ID ENSG00000111087 ENSG00000107882
Uniprot IDs B4DNF7 P08151 A0A223LX15 Q9UMX1
PDB IDs 2GLI 4BLB 4KMD 5OM0 1M1L 4BL8 4BL9 4BLA 4BLB 4BLD 4KM8 4KM9 4KMD 4KMH
Enriched GO Terms of Interacting Partners?
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