STK39 and TSC22D2

Number of citations of the paper that reports this interaction (PubMedID 27337956)
18

Data Source:
BioGRID (two hybrid)

		STK39	TSC22D2
Description		serine/threonine kinase 39	TSC22 domain family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Protein Kinase Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
	Biological Process	Activation Of MAPK Activity Protein Phosphorylation Regulation Of Mitotic Cell Cycle Regulation Of Blood Pressure Positive Regulation Of T Cell Chemotaxis Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Signal Transduction By Protein Phosphorylation Signal Transduction By Trans-phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Positive Regulation Of Ion Transmembrane Transporter Activity Intracellular Signal Transduction Maintenance Of Lens Transparency Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Positive Regulation Of Potassium Ion Transport Protein Autophosphorylation Regulation Of Inflammatory Response Ion Homeostasis Cellular Hypotonic Response Negative Regulation Of Pancreatic Juice Secretion Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Creatine Transmembrane Transporter Activity Cellular Response To Chemokine Negative Regulation Of Sodium Ion Transmembrane Transporter Activity	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 19114657) Body mass index ( 28552196 28892062) Macular thickness ( 30535121) Metabolite levels ( 23823483) Parkinson's disease ( 21292315 25064009 27182965 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Weight ( 28552196)	Adiponectin levels ( 22479202) Cognitive decline rate in late mild cognitive impairment ( 26252872) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701)
Interacting Genes		14 interacting genes: AATK GSN HSPH1 MAPK14 MBP OTOF PRKCQ RELT SLC12A1 SLC12A2 SLC12A6 SPP1 TSC22D2 WNK4	43 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL LRRC6 MED13 MPDZ MSH3 MTIF2 NGRN NRBP1 OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251
Entrez ID		27347	9819
HPRD ID		09627	11101
Ensembl ID		ENSG00000198648	ENSG00000196428
Uniprot IDs		Q9UEW8	B4DN36 O75157
PDB IDs
Enriched GO Terms of Interacting Partners?
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