TUBGCP4 and PAK5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		TUBGCP4	PAK5
Description		tubulin gamma complex associated protein 4	p21 (RAC1) activated kinase 5
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GO Annotations	Cellular Component	Spindle Pole Equatorial Microtubule Organizing Center Gamma-tubulin Complex Centrosome Cytosol Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Membrane Recycling Endosome	Nucleoplasm Cytoplasm Mitochondrion Synapse
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Microtubule Nucleation By Interphase Microtubule Organizing Center Protein-containing Complex Assembly	Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Signal Transduction Regulation Of Mitotic Cell Cycle Learning Memory Locomotory Behavior Cell Proliferation Cell Migration Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Activation of RAC1
Drugs
Diseases
GWAS		Glycine levels ( 30837465) HDL cholesterol ( 30275531) Triglycerides ( 30275531)	Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
Interacting Genes		26 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 LZTR1 MAD1L1 NUDT3 PAK5 RNF146 RPRD1B SDSL STN1 TRIM27 TUBG1 USHBP1 VIM	21 interacting genes: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FHL3 GCC1 INKA1 LENG1 LZTS2 PDLIM7 PRPF31 PSMF1 RAC1 SORBS3 TUBGCP4 UXT
Entrez ID		27229	57144
HPRD ID		10616	06423
Ensembl ID		ENSG00000137822	ENSG00000101349
Uniprot IDs		Q9UGJ1	B0AZM9 Q9P286
PDB IDs		3RIP	2F57
Enriched GO Terms of Interacting Partners?
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