NDOR1 and TCHP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NDOR1	TCHP
Description		NADPH dependent diflavin oxidoreductase 1	trichoplein keratin filament binding
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex Ciliary Transition Fiber
	Molecular Function	NADPH-hemoprotein Reductase Activity Protein Binding FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Flavin Adenine Dinucleotide Binding NADP Binding	Protein Binding
	Biological Process	Cell Death Iron-sulfur Cluster Assembly Cellular Response To Menadione Oxidation-reduction Process	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways		Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		8 interacting genes: CCDC33 CYCS DLG4 EFHC2 MTUS2 PMPCA TCF4 TCHP	23 interacting genes: CCDC172 CCDC85B CDR2 DYDC1 IFFO1 KCTD17 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM
Entrez ID		27158	84260
HPRD ID		10444	14403
Ensembl ID		ENSG00000188566	ENSG00000139437
Uniprot IDs		Q9UHB4	A0A024RBM9 Q9BT92
PDB IDs		4H2D
Enriched GO Terms of Interacting Partners?
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