AKTIP and DZIP3

Number of citations of the paper that reports this interaction (PubMedID 19549727)
67

Data Source:
BioGRID (two hybrid)

		AKTIP	DZIP3
Description		AKT interacting protein	DAZ interacting zinc finger protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane HOPS Complex FHF Complex	Cytoplasm
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport	Protein Polyubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 25673412) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		26 interacting genes: AKT1 ASS1 CEP126 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MARCHF5 MATR3 PDPK1 POLA2 RPA1 TRIM23 TRIM41 TWNK UTP14A VPS16 VPS18 VPS41	44 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BIRC2 BIRC3 CARM1 CEP63 DAZ1 GRIP1 GTF2H2C_2 HNRNPF HNRNPUL1 HOTAIR NCOR1 PCGF3 RAD18 RBM4B RNF38 RUNX1 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765
Entrez ID		64400	9666
HPRD ID		07467	10562
Ensembl ID		ENSG00000166971	ENSG00000198919
Uniprot IDs		A0A024R6S6 A0A024R6T5 Q9H8T0	Q86Y13
PDB IDs
Enriched GO Terms of Interacting Partners?
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