BEX3 and CCDC116

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		BEX3	CCDC116
Description		brain expressed X-linked 3	coiled-coil domain containing 116
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Cytoplasm Centrosome
	Molecular Function	Nerve Growth Factor Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Multicellular Organism Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways		NADE modulates death signalling
Drugs
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Ulcerative colitis ( 28067908)
Interacting Genes		29 interacting genes: AIMP2 AKAP8L CACYBP CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 FSD2 GOLGA8EP GOLGA8F MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 SIVA1 SMPD1 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSC1 USHBP1 VTA1 YWHAE	11 interacting genes: BEX3 CCDC85B CEP44 FAM9B KRTAP4-12 MDFI MTUS2 SLC2A4 TFIP11 TRAF1 USHBP1
Entrez ID		27018	164592
HPRD ID		02291	08203
Ensembl ID		ENSG00000166681	ENSG00000161180
Uniprot IDs		Q00994	Q8IYX3
PDB IDs		1SA6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?