EPC2 and EZH2

  • Number of citations of the paper that reports this interaction (PubMedID 22659877)
  • 74
  • Data Source:
  • BioGRID (unspecified method)

EPC2

EZH2

Description enhancer of polycomb homolog 2 enhancer of zeste 2 polycomb repressive complex 2 subunit
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronotype ( 30696823)
  • Colorectal or endometrial cancer ( 26621817)
  • Crohn's disease ( 28067908)
  • Familial squamous cell lung carcinoma ( 29924316)
  • Height ( 25282103 31562340)
  • Inflammatory bowel disease ( 28067908)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes 2 interacting genes: EED EZH2 74 interacting genes: AKT1 ATP1A1 ATP1B1 ATRX BCL11A BRCA1 C7orf25 CCDC85B CDK2 CDK6 CDKN2B-AS1 CEP63 CRY2 DELEC1 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 FBXW7 GADD45G GTF3C1 H1-1 H3-4 H3C1 HDAC1 HOTAIR JAK2 KAT2B KDM1A KLHDC2 LATS2 MAP3K20 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 MUC1 MYCN NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRDM14 PRMT5 PSMB6 RASA1 RBL2 RELA RELB RIN3 RPN2 RPS6KA5 SIRT1 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 TRIM28 USP7 VAV1 WDR61 WSB2 ZMYND11
Entrez ID 26122 2146
HPRD ID 13274 03342
Ensembl ID ENSG00000135999 ENSG00000106462
Uniprot IDs Q52LR7 A0A090N8E9 Q15910 S4S3R8
PDB IDs 2C6V 4MI0 4MI5 5GSA 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5LS6 5U5T 5U62 5WG6 5WUK 6C23 6C24
Enriched GO Terms of Interacting Partners?
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