GPSM1 and INSC

Number of citations of the paper that reports this interaction (PubMedID 16458856)
9

Data Source:
HPRD (in vivo)

		GPSM1	INSC
Description		G protein signaling modulator 1	INSC spindle orientation adaptor protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex	Plasma Membrane Cell Cortex Protein-containing Complex
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding	Protein Binding Protein Domain Specific Binding Protein Binding, Bridging
	Biological Process	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Nervous System Development Asymmetric Cell Division Cell Differentiation Regulation Of Protein Stability
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)	Expressive vocabulary in infants ( 25226531) Heel bone mineral density ( 30598549 28869591) Menarche (age at onset) ( 23667675) Obesity-related traits ( 23251661)
Interacting Genes		12 interacting genes: CCDC158 DAZAP2 GNAI1 GNAI3 INSC KANK2 MAP1LC3A OSTM1 TRIP13 USHBP1 USP9X ZBED1	5 interacting genes: GPSM1 GPSM2 LNX1 PARD3 PARD3B
Entrez ID		26086	387755
HPRD ID		17075	18803
Ensembl ID		ENSG00000160360	ENSG00000188487
Uniprot IDs		A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5	Q1MX18
PDB IDs			3SF4
Enriched GO Terms of Interacting Partners?
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