NELFB and MGST1

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		NELFB	MGST1
Description		negative elongation factor complex member B	microsomal glutathione S-transferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm NELF Complex	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Apical Part Of Cell
	Molecular Function	RNA Binding Protein Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding Glutathione Binding Prostaglandin-E Synthase Activity
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Cell Proliferation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Stem Cell Differentiation Positive Regulation Of Viral Transcription Negative Regulation Of Stem Cell Differentiation	Prostaglandin Biosynthetic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Response To Drug Neutrophil Degranulation Oxidation-reduction Process Cellular Response To Lipid Hydroperoxide Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation NTRK3 as a dependence receptor	Glutathione conjugation Aflatoxin activation and detoxification Neutrophil degranulation
Drugs			Glutathione
Diseases
GWAS			Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Visceral fat ( 22589738)
Interacting Genes		15 interacting genes: BRCA1 CEBPE DENR ESR1 EXOSC2 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFE NTRK3 RAD51	2 interacting genes: LTC4S NELFB
Entrez ID		25920	4257
HPRD ID		10845	00705
Ensembl ID		ENSG00000188986	ENSG00000008394
Uniprot IDs		Q8WX92	A0A024RAX2 P10620
PDB IDs		6GML
Enriched GO Terms of Interacting Partners?
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