NELFB and KHDRBS3

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		NELFB	KHDRBS3
Description		negative elongation factor complex member B	KH RNA binding domain containing, signal transduction associated 3
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm NELF Complex	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Cell Proliferation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Stem Cell Differentiation Positive Regulation Of Viral Transcription Negative Regulation Of Stem Cell Differentiation	MRNA Processing Viral Process Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation NTRK3 as a dependence receptor	PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS			Chronotype ( 30696823) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		15 interacting genes: BRCA1 CEBPE DENR ESR1 EXOSC2 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFE NTRK3 RAD51	33 interacting genes: BAHD1 CACNA1A CCDC33 DMRT3 FBXO7 FUS HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LNX1 MARK4 NCOA5 NELFB NUDT18 PPP1R13B PRMT1 PRPF31 PSMF1 PTBP2 RBBP6 RBM7 RBMX RBMY1A1 SGSM2 SIAH1 SNRPC SRSF9 U2AF2 YTHDC1 ZNF408 ZNF688
Entrez ID		25920	10656
HPRD ID		10845	10007
Ensembl ID		ENSG00000188986	ENSG00000131773
Uniprot IDs		Q8WX92	O75525
PDB IDs		6GML	5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?
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