BRMS1 and NMI

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid, two hybrid)

		BRMS1	NMI
Description		BRMS1 transcriptional repressor and anoikis regulator	N-myc and STAT interactor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Transcription Coregulator Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Transcription By RNA Polymerase II Inflammatory Response JAK-STAT Cascade Negative Regulation Of Interferon-alpha Biosynthetic Process Negative Regulation Of Interferon-beta Biosynthetic Process Negative Regulation Of Innate Immune Response Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Protein K48-linked Ubiquitination Regulation Of Nucleic Acid-templated Transcription
Pathways		HDACs deacetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Blood protein levels ( 28240269)
Interacting Genes		48 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	54 interacting genes: BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EXOSC5 GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 TRAF5 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		25855	9111
HPRD ID		05879	04632
Ensembl ID		ENSG00000174744	ENSG00000123609
Uniprot IDs		G5E9I4 Q9HCU9	Q13287
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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