BRMS1 and PFDN5

Number of citations of the paper that reports this interaction (PubMedID 16919237)
34

Data Source:
HPRD (two hybrid, in vivo)

		BRMS1	PFDN5
Description		BRMS1 transcriptional repressor and anoikis regulator	prefoldin subunit 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus Cytoplasm Cytosol Prefoldin Complex Intermediate Filament Cytoskeleton
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Transcription Corepressor Activity Protein Binding Unfolded Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Regulation Of Transcription, DNA-templated Protein Folding Negative Regulation Of Transcription, DNA-templated Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		HDACs deacetylate histones	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)
Interacting Genes		48 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	13 interacting genes: BRMS1 CALCOCO2 GLRX3 IKBKG IKZF3 ITSN1 MYC PFDN6 PSME3 TP73 TRIM28 TUBA1B TUBA3C
Entrez ID		25855	5204
HPRD ID		05879	05359
Ensembl ID		ENSG00000174744	ENSG00000123349
Uniprot IDs		G5E9I4 Q9HCU9	Q99471
PDB IDs		2XUS 4AUV	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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