MOB4 and PLEKHM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MOB4	PLEKHM1
Description		MOB family member 4, phocein	pleckstrin homology and RUN domain containing M1
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Golgi Cisterna Membrane Neuronal Cell Body Dendritic Spine Perinuclear Region Of Cytoplasm	Nucleolus Lysosomal Membrane Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	Metal Ion Binding
	Biological Process		Autophagy Protein Transport Lysosome Localization Intracellular Signal Transduction Positive Regulation Of Bone Resorption Positive Regulation Of Ruffle Assembly
Pathways
Drugs
Diseases
GWAS		Allergic rhinitis ( 31361310) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 28067908) Schizophrenia ( 29483656)	Alcohol use disorder (total score) ( 30336701) Cognitive function ( 28093568) Epithelial ovarian cancer ( 25581431) Hip circumference ( 28552196) Male-pattern baldness ( 29146897 28196072) Neuroticism ( 29255261) Parkinson's disease ( 20070850) Remission after SSRI treatment in MDD or neuroticism ( 29559929)
Interacting Genes		32 interacting genes: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PPIL3 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2	8 interacting genes: BID EIF2S2 GADD45G MAPK6 MOB4 MUC2 PAFAH1B3 SERPINB9
Entrez ID		25843	9842
HPRD ID		10165	11439
Ensembl ID		ENSG00000115540	ENSG00000225190
Uniprot IDs		A0A024R3X9 Q9Y3A3	Q9Y4G2
PDB IDs		5YF4	5DPR 5DPS 5DPT 5DPW
Enriched GO Terms of Interacting Partners?
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