GABRR1 and SLC6A9

Number of citations of the paper that reports this interaction (PubMedID 10625616)
10

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		GABRR1	SLC6A9
Description		gamma-aminobutyric acid type A receptor subunit rho1	solute carrier family 6 member 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Glutamatergic Synapse GABA-ergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Membrane Integral Component Of Synaptic Vesicle Membrane Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	GABA-A Receptor Activity Chloride Channel Activity Ligand-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Glycine:sodium Symporter Activity
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Regulation Of Postsynaptic Membrane Potential Regulation Of Presynaptic Membrane Potential Chloride Transmembrane Transport	Neurotransmitter Uptake Amino Acid Transmembrane Transport Transport Glycine Secretion, Neurotransmission
Pathways		GABA receptor activation	Na+/Cl- dependent neurotransmitter transporters
Drugs		Temazepam Lindane Picrotoxin Adinazolam Midazolam Flurazepam Halazepam Diazepam Oxazepam Triazolam Estazolam Bromazepam Clotiazepam Fludiazepam Prazepam Quazepam Cinolazepam Nitrazepam	Glycine
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder and schizophrenia ( 20889312) Diabetic kidney disease in type 2 diabetes ( 29703844) Early diabetic kidney disease in type 2 diabetes ( 29703844) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)	Attention deficit hyperactivity disorder or cannabis use ( 30610198) Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular volume ( 29403010)
Interacting Genes		10 interacting genes: CSNK2A1 GABRR2 MAP1B MAPK1 P2RX2 PRKACA PRKCA PRKG1 SLC6A9 SQSTM1	3 interacting genes: GABRR1 PRKCA STX1A
Entrez ID		2569	6536
HPRD ID		15921	03010
Ensembl ID		ENSG00000146276	ENSG00000196517
Uniprot IDs		P24046	B7Z3W8 B7Z589 P48067
PDB IDs
Enriched GO Terms of Interacting Partners?
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