GABRR1 and GABRR2

Number of citations of the paper that reports this interaction (PubMedID 9153229)
6

Data Source:
HPRD (in vitro)

		GABRR1	GABRR2
Description		gamma-aminobutyric acid type A receptor subunit rho1	gamma-aminobutyric acid type A receptor subunit rho2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Glutamatergic Synapse GABA-ergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane GABA-ergic Synapse
	Molecular Function	GABA-A Receptor Activity Chloride Channel Activity Ligand-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	GABA-A Receptor Activity Chloride Channel Activity Protein Domain Specific Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Regulation Of Postsynaptic Membrane Potential Regulation Of Presynaptic Membrane Potential Chloride Transmembrane Transport	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Visual Perception Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Regulation Of Postsynaptic Membrane Potential Chloride Transmembrane Transport
Pathways		GABA receptor activation	GABA receptor activation
Drugs		Temazepam Lindane Picrotoxin Adinazolam Midazolam Flurazepam Halazepam Diazepam Oxazepam Triazolam Estazolam Bromazepam Clotiazepam Fludiazepam Prazepam Quazepam Cinolazepam Nitrazepam	Temazepam Adinazolam Midazolam Flurazepam Halazepam Diazepam Oxazepam Triazolam Estazolam Bromazepam Clotiazepam Fludiazepam Prazepam Quazepam Cinolazepam Nitrazepam
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder and schizophrenia ( 20889312) Diabetic kidney disease in type 2 diabetes ( 29703844) Early diabetic kidney disease in type 2 diabetes ( 29703844) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)	Third ventricle volume ( 31530798)
Interacting Genes		10 interacting genes: CSNK2A1 GABRR2 MAP1B MAPK1 P2RX2 PRKACA PRKCA PRKG1 SLC6A9 SQSTM1	5 interacting genes: CSNK2A1 GABRR1 MAP1B PRKCA SQSTM1
Entrez ID		2569	2570
HPRD ID		15921	15922
Ensembl ID		ENSG00000146276	ENSG00000111886
Uniprot IDs		P24046	B4DER2 P28476
PDB IDs
Enriched GO Terms of Interacting Partners?
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