XRCC6 and SNU13

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		XRCC6	SNU13
Description		X-ray repair cross complementing 6	small nuclear ribonucleoprotein 13
Image
GO Annotations	Cellular Component	Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Extracellular Region Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytosol Membrane Protein-containing Complex Protein-DNA Complex Secretory Granule Lumen Ku70:Ku80 Complex Nonhomologous End Joining Complex Ficolin-1-rich Granule Lumen	Dense Fibrillar Component Nucleus Nucleoplasm U4atac SnRNP Nucleolus Box C/D SnoRNP Complex Small-subunit Processome Protein-containing Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	DNA Binding DNA Helicase Activity Damaged DNA Binding Double-stranded DNA Binding Double-stranded Telomeric DNA Binding RNA Binding Protein Binding ATP Binding Protein C-terminus Binding Cyclin Binding Telomeric DNA Binding Transcription Regulatory Region DNA Binding Protein-containing Complex Binding 5'-deoxyribose-5-phosphate Lyase Activity	RNA Binding Protein Binding SnoRNA Binding U4 SnRNA Binding U4atac SnRNA Binding U3 SnoRNA Binding Box C/D SnoRNA Binding ATPase Binding
	Biological Process	Telomere Maintenance Activation Of Innate Immune Response DNA Ligation Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination Brain Development Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Neutrophil Degranulation Innate Immune Response Positive Regulation Of Protein Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Smooth Muscle Cell Proliferation Cellular Hyperosmotic Salinity Response Cellular Response To Gamma Radiation Cellular Response To X-ray Establishment Of Integrated Proviral Latency Double-strand Break Repair Via Classical Nonhomologous End Joining	MRNA Splicing, Via Spliceosome Maturation Of LSU-rRNA Box C/D SnoRNP Assembly RRNA Processing Single Fertilization Maturation Of SSU-rRNA
Pathways		2-LTR circle formation Cytosolic sensors of pathogen-associated DNA IRF3-mediated induction of type I IFN Nonhomologous End-Joining (NHEJ) Neutrophil degranulation	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs			Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Anisomycin
Diseases
GWAS		Breast cancer ( 29059683) Neuroticism ( 29255261) Pulse pressure ( 28135244)
Interacting Genes		131 interacting genes: ABCD4 ABL1 ACD ADCY7 APEX1 AR ARAP1 ATP23 ATP6V1E1 BARD1 BAZ1A BTG1 CAPN11 CBX5 CCNA1 CCT3 CD40 CDCA5 CDK2 CDKN1A CEBPA CENPU CHAF1A CHEK1 CLTC CLU CMTM6 COIL COPB1 CREBBP CSNK2A1 CTBP2 DLX2 DNTT EFNA1 EGFR EID1 ELF3 EP300 EPS8 ETS1 FMNL1 GAL3ST4 GSE1 GZMA GZMB HERPUD1 HMGA2 HOXB7 HOXC4 HOXD4 HSF1 HTT ILVBL JPT2 KAT2A KAT2B KIAA0408 LIG3 MAP2K5 MAP4K2 MAPK8 MRE11 MSX2 NAA15 NCF4 NCL NCOA6 NIT1 NOTCH1 PAEP PAFAH1B3 PARP1 PCNA PDK1 PDPK1 PDX1 PECAM1 PGAM1 PGR PIN1 PLGRKT PNRC2 POR POU2F1 POU2F2 PRKDC PRPF40A PTTG1 QRSL1 RASA1 RBBP4 RGS2 RNF126 RNF146 RPLP1 RPS10 RRAS2 RUNX2 SDHC SELENOF SERPINA2 SERPINB9 SET SGO1 SIRT3 SKIL SMAD3 SMAD7 SNTA1 SNU13 SPARC SUMO2 TAC1 TADA3 TBCD TCF4 TERF2 TERF2IP TERT TOP1 TP53 UBC VAV1 VBP1 WBP4 WRN XRCC5 YWHAZ ZBTB7A ZNF512B	14 interacting genes: CDKN2C CHST1 GTF3C1 HSPB2 LRIF1 MAP1LC3B NUFIP1 POLA2 PPIH RAD17 RBM10 RHOU SNW1 XRCC6
Entrez ID		2547	4809
HPRD ID		01071	03197
Ensembl ID		ENSG00000196419	ENSG00000100138
Uniprot IDs		A0A024R1N4 B1AHC9 B4DE32 B4E356 P12956	P55769 Q6FHM6
PDB IDs		1JEQ 1JEY 1JJR 3RZX 5Y3R 6ERF 6ERG 6ERH	1E7K 2JNB 2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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