WASHC2C and WASHC5

Number of citations of the paper that reports this interaction (PubMedID 20923837)
100

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		WASHC2C	WASHC5
Description		WASH complex subunit 2C	WASH complex subunit 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Endosome Early Endosome Cytosol Plasma Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle WASH Complex	Nucleoplasm Early Endosome Endoplasmic Reticulum Cytosol Neuron Projection Neuronal Cell Body WASH Complex
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding Retromer Complex Binding	Protein Binding
	Biological Process	Protein Transport Protein Localization To Endosome Retrograde Transport, Endosome To Golgi Regulation Of Substrate Adhesion-dependent Cell Spreading Retrograde Transport, Endosome To Plasma Membrane Negative Regulation Of Barbed-end Actin Filament Capping	Oocyte Maturation Positive Regulation Of Neuron Projection Development Protein Transport Endosomal Transport Cellular Protein-containing Complex Localization Polar Body Extrusion After Meiotic Divisions Regulation Of Actin Nucleation Spindle Assembly Involved In Meiosis Regulation Of Vesicle Size
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		2 interacting genes: ATXN1 WASHC5	2 interacting genes: WASHC1 WASHC2C
Entrez ID		253725	9897
HPRD ID		11094	13786
Ensembl ID		ENSG00000172661	ENSG00000164961
Uniprot IDs		A0A096LPC5 A8K5W5 B3KMC4 Q9Y4E1	E7EQI7 Q12768
PDB IDs
Enriched GO Terms of Interacting Partners?
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