TFIP11 and SNW1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TFIP11	SNW1
Description		tuftelin interacting protein 11	SNW domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Nuclear Speck Extracellular Matrix U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Cyclin/CDK Positive Transcription Elongation Factor Complex Nuclear Matrix Nuclear Body Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding	Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Notch Binding Protein Binding Enzyme Binding Nuclear Hormone Receptor Binding Vitamin D Receptor Binding Retinoic Acid Receptor Binding SMAD Binding Androgen Receptor Binding
	Biological Process	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome RNA Processing Biomineral Tissue Development Negative Regulation Of Protein Complex Assembly Protection From Non-homologous End Joining At Telomere Negative Regulation Of Protein Binding Negative Regulation Of DNA Ligase Activity Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Positive Regulation Of Transcription Of Notch Receptor Target Viral Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation By Host Of Viral Transcription Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Neurogenesis Positive Regulation Of Histone H3-K4 Methylation Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Retinoic Acid
Pathways		mRNA Splicing - Major Pathway	Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells NOTCH1 Intracellular Domain Regulates Transcription NOTCH1 Intracellular Domain Regulates Transcription SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway mRNA Splicing - Major Pathway RUNX3 regulates NOTCH signaling RUNX3 regulates NOTCH signaling NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription
Drugs
Diseases
GWAS			Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
Interacting Genes		128 interacting genes: ABI2 AIMP2 ANKRD11 ARHGEF9 ARMC7 ARMCX1 ARNT2 ATP5PO AXIN1 BCL6 BMF C1orf109 C2CD6 CARD9 CCDC116 CCDC121 CCDC146 CCDC151 CCDC196 CCDC42 CCDC68 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CENPU CEP57 CEP57L1 CFAP206 COQ8A COX5B DGCR6 DISC1 EAF2 EIF3A FAM13C FAM156A FAM161A FAM50B FANCG GCC1 GEM GNG4 GOLGA1 GOLGA2 GPS2 GRAP2 HAUS1 HMG20B HOOK1 IKBIP IL16 IMP3 KANSL1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5L LENG1 LIN37 LMO1 LMO4 LSM3 LSP1P3 MCM7 MDM2 METTL17 MTFR2 NDC80 NDE1 NDN NFU1 OIP5 PBX4 PCM1 PDE4DIP POLL POLR1C PPP1R16A PPP1R16B PPP1R18 PRPF31 PSTPIP1 RCOR3 RHNO1 RNF6 RRP7A RXRB S100P SAP30BP SCNM1 SFR1 SH2D4A SH3GLB1 SMARCB1 SMARCE1 SNRPB SNW1 SNX20 SSX2IP STRN SYCE1 TCAF1 TDP2 TFPT THAP7 THAP8 TNNT1 TP53 TRAF3IP3 TRAPPC4 TSHZ3 TSPYL4 TUFT1 TXLNA USP6 USP7 VPS37C ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZSCAN12	61 interacting genes: ACTN2 ASCC2 CEP55 CIR1 CXorf56 DAXX EP300 GOLGA2 HDAC2 IKBKG IKZF1 JDP2 KRT40 LRP2BP LZTS2 MAGEA1 MAPK6 MEN1 MFAP1 MSL1 MTUS2 NCOA1 NCOR1 NCOR2 NOTCH1 NOTCH3 NR0B1 NR0B2 OCLN PABPN1 PCBD2 PGR PPIL1 PRKAA2 RARA RB1 RBL1 RBL2 RBPJ RINT1 RXRA SART1 SIN3A SIRT1 SKI SMAD2 SMAD3 SMAD4 SNRNP200 SNU13 TEX11 TFIP11 TNNT1 TOP1 TRAF1 TRIM15 TTC14 VAV2 VDR VPS39 ZSCAN1
Entrez ID		24144	22938
HPRD ID		11628	04340
Ensembl ID		ENSG00000100109	ENSG00000100603
Uniprot IDs		A0A024R1I7 Q9UBB9	G3V3A4 Q13573
PDB IDs			5MQF 5XJC 5YZG 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV
Enriched GO Terms of Interacting Partners?
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