FKBP8 and CLCN1

Number of citations of the paper that reports this interaction (PubMedID 27580824)
4

Data Source:
BioGRID (pull down, affinity chromatography technology)

		FKBP8	CLCN1
Description		FKBP prolyl isomerase 8	chloride voltage-gated channel 1
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Sarcolemma
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Binding Involved In Protein Folding Metal Ion Binding Disordered Domain Specific Binding	Voltage-gated Chloride Channel Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Viral Process Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process	Chloride Transport Muscle Contraction Neuronal Action Potential Propagation Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Ub-specific processing proteases	Stimuli-sensing channels
Drugs
Diseases			Myotonia congenita, including: Autosomal dominant myotonia congenita (Thomsen disease); Autosomal recessive myotonia congenita (Becker disease); Fluctuating myotonia congenita; Myotonia levoir
GWAS		Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)
Interacting Genes		17 interacting genes: ANKMY2 ARHGEF5 ATP13A2 BCL2 BCL2L1 BNIPL CLCN1 EGFR EGLN1 MAPK14 MTOR PPP3CA PSMC1 PSMD2 RHEB TERF1 VHL	5 interacting genes: AHSA1 APPBP2 FAM9B FKBP8 STIP1
Entrez ID		23770	1180
HPRD ID		05327	00320
Ensembl ID		ENSG00000105701	ENSG00000188037
Uniprot IDs		A0A024R7P2 B2R8G6 Q14318	P35523
PDB IDs		2AWG 2D9F 2F2D 2MF9 3EY6 5MGX	6COY 6COZ 6QV6 6QVB 6QVC 6QVD 6QVU
Enriched GO Terms of Interacting Partners?
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