CLCN1 and FKBP8

Number of citations of the paper that reports this interaction (PubMedID 27580824)
4

Data Source:
BioGRID (pull down, affinity chromatography technology)

		CLCN1	FKBP8
Description		chloride voltage-gated channel 1	FKBP prolyl isomerase 8
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Sarcolemma	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Voltage-gated Chloride Channel Activity Protein Binding Protein Homodimerization Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Binding Involved In Protein Folding Metal Ion Binding Disordered Domain Specific Binding
	Biological Process	Chloride Transport Muscle Contraction Neuronal Action Potential Propagation Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport	Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Viral Process Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process
Pathways		Stimuli-sensing channels	Ub-specific processing proteases
Drugs
Diseases		Myotonia congenita, including: Autosomal dominant myotonia congenita (Thomsen disease); Autosomal recessive myotonia congenita (Becker disease); Fluctuating myotonia congenita; Myotonia levoir
GWAS			Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)
Interacting Genes		5 interacting genes: AHSA1 APPBP2 FAM9B FKBP8 STIP1	17 interacting genes: ANKMY2 ARHGEF5 ATP13A2 BCL2 BCL2L1 BNIPL CLCN1 EGFR EGLN1 MAPK14 MTOR PPP3CA PSMC1 PSMD2 RHEB TERF1 VHL
Entrez ID		1180	23770
HPRD ID		00320	05327
Ensembl ID		ENSG00000188037	ENSG00000105701
Uniprot IDs		P35523	A0A024R7P2 B2R8G6 Q14318
PDB IDs		6COY 6COZ 6QV6 6QVB 6QVC 6QVD 6QVU	2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?
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