TRIM29 and FBXL19

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		TRIM29	FBXL19
Description		tripartite motif containing 29	F-box and leucine rich repeat protein 19
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GO Annotations	Cellular Component	Lysosome Adherens Junction	Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	P53 Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	Protein Binding Zinc Ion Binding Unmethylated CpG Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus	Protein Polyubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		Interferon gamma signaling	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Stroke (pediatric) ( 22990015)	Diastolic blood pressure ( 28135244 27841878) Mean corpuscular volume ( 27863252) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878)
Interacting Genes		47 interacting genes: ATM CARD9 CDC34 CEP70 CRACR2A DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MYO15B POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM	4 interacting genes: CBFA2T2 CREBBP TRIM27 TRIM29
Entrez ID		23650	54620
HPRD ID		10280	12366
Ensembl ID		ENSG00000137699	ENSG00000099364
Uniprot IDs		A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134	H3BVB1 Q6PCT2
PDB IDs		2CSV	6ASB
Enriched GO Terms of Interacting Partners?
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