TRIM29 and DMRT1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		TRIM29	DMRT1
Description		tripartite motif containing 29	doublesex and mab-3 related transcription factor 1
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GO Annotations	Cellular Component	Lysosome Adherens Junction	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	P53 Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Male Germ Cell Proliferation Spermatogenesis Germ Cell Migration Male Sex Determination Intracellular Signal Transduction Negative Regulation Of Meiotic Nuclear Division Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Male Sex Differentiation Oocyte Development Sertoli Cell Differentiation Sertoli Cell Development Positive Regulation Of Meiosis I Regulation Of Nodal Signaling Pathway Positive Regulation Of Male Gonad Development
Pathways		Interferon gamma signaling
Drugs
Diseases			46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS		Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Stroke (pediatric) ( 22990015)	Dupuytren's disease ( 28886342) Major depressive disorder ( 23377640) Medial orbital frontal cortex volume ( 31530798) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Testicular cancer ( 21551455) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 28604728 28604732 23666239 23666240) Uterine fibroids ( 30194396)
Interacting Genes		47 interacting genes: ATM CARD9 CDC34 CEP70 CRACR2A DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MYO15B POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM	1 interacting genes: TRIM29
Entrez ID		23650	1761
HPRD ID		10280	03885
Ensembl ID		ENSG00000137699	ENSG00000137090
Uniprot IDs		A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134	Q9Y5R6
PDB IDs		2CSV	4YJ0
Enriched GO Terms of Interacting Partners?
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