LDOC1 and DPF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LDOC1	DPF2
Description		LDOC1 regulator of NFKB signaling	double PHD fingers 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Histone Acetyltransferase Complex Nuclear Chromatin Nucleus Nucleoplasm Centrosome Cytosol Intracellular Membrane-bounded Organelle NBAF Complex
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Corepressor Activity Histone Acetyltransferase Activity Protein Binding Histone Binding Metal Ion Binding H3K9me3 Modified Histone Binding Lysine-acetylated Histone Binding
	Biological Process	Maternal Placenta Development Negative Regulation Of Cell Proliferation Maternal Process Involved In Parturition Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Regulation Of Growth Hormone Activity	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Nervous System Development Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Apoptotic Signaling Pathway Negative Regulation Of Myeloid Progenitor Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Urate levels ( 31578528)
Interacting Genes		68 interacting genes: AATF ABLIM1 AEBP2 AP1M1 ATF4 ATP6V1G1 BARD1 C1orf109 CCDC33 CCDC85B CEBPE CTNNBL1 DPF2 DPPA4 FAM107A FAM193B FAM50B FAM90A1 FOSL1 FXR2 GNL3L HAUS1 HDAC4 HGS IKZF3 IKZF5 INPP1 KRT15 KRT18 LATS1 LENG1 LNX1 MEAF6 MFAP1 MYC MZF1 NOD2 NRIP1 NXF1 PEG10 PLEKHF2 POLL PRPF31 PSMA1 PSMF1 RAB29 RNF6 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 TASOR2 TBC1D7 TLE5 TMSB4XP1 TNNT1 TTC23 UTP14A WT1 ZBTB16 ZBTB24 ZGPAT ZNF250 ZNF408 ZNF564 ZNF688 ZNF774	11 interacting genes: FHL2 H3-4 H3C1 H4C1 LDOC1 LNX1 NFKB2 REL RELB UPF2 ZNF212
Entrez ID		23641	5977
HPRD ID		02322	03394
Ensembl ID		ENSG00000182195	ENSG00000133884
Uniprot IDs		O95751	A0A024R582 J3KMZ8 Q92785
PDB IDs			3IUF 5B79 5VDC
Enriched GO Terms of Interacting Partners?
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