FOSL2 and DNAJA3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FOSL2	DNAJA3
Description		FOS like 2, AP-1 transcription factor subunit	DnaJ heat shock protein family (Hsp40) member A3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Actin Filament Extrinsic Component Of Plasma Membrane Cell Junction Neuromuscular Junction Intracellular Membrane-bounded Organelle Postsynaptic Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	Protein Binding ATP Binding Hsp70 Protein Binding GTPase Regulator Activity Metal Ion Binding Unfolded Protein Binding
	Biological Process	Keratinocyte Development Regulation Of Transcription By RNA Polymerase II Cell Death Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Mitochondrial DNA Replication Protein Folding Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Cell Aging Negative Regulation Of Cell Proliferation Response To Heat T Cell Differentiation In Thymus Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Allergic rhinitis ( 30013184) Blond vs. brown/black hair color ( 30531825) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Soluble interleukin-2 receptor subunit alpha ( 26293465) Systolic blood pressure ( 28135244 30578418) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Type 1 diabetes ( 21980299)	Erectile dysfunction ( 30583798) Schizophrenia ( 28991256) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		14 interacting genes: CREB5 DDIT3 DNAJA3 DNMT3L EP300 FHL3 GMCL1 GOPC JUN JUNB JUND LUZP4 SRA1 TRAF1	40 interacting genes: ATXN1 BRCA1 C2CD6 CARM1 COIL FAM131C FAM214B FBXO7 FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 IFNGR2 INPP5J JAK2 KDM1A KRAS MCPH1 MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 RAD51 RASA1 RELA RNF34 SMAD9 SMARCB1 STK16 TCF19 USP7 VHL ZBTB22
Entrez ID		2355	9093
HPRD ID		03343	09758
Ensembl ID		ENSG00000075426	ENSG00000103423
Uniprot IDs		P15408 Q9H5M2	B3KM81 Q53G26 Q59E88 Q96EY1
PDB IDs			2CTT 2DN9
Enriched GO Terms of Interacting Partners?
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