FOSB and JUNB

Number of citations of the paper that reports this interaction (PubMedID 12371906)
41

Data Source:
HPRD (in vitro)

		FOSB	JUNB
Description		FosB proto-oncogene, AP-1 transcription factor subunit	JunB proto-oncogene, AP-1 transcription factor subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Chromatin Nuclear Chromatin Nucleoplasm Transcription Factor Complex Transcription Factor AP-1 Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Female Pregnancy Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Morphine Positive Regulation Of Transcription By RNA Polymerase II Response To Corticosterone Response To CAMP Cellular Response To Calcium Ion	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Response To Radiation Response To Mechanical Stimulus Response To Organic Substance Cytokine-mediated Signaling Pathway Osteoclast Differentiation Response To Lipopolysaccharide Cellular Response To Hormone Stimulus Cellular Response To Stress Osteoblast Proliferation Response To Cytokine Regulation Of Cell Proliferation Response To Drug Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion
Pathways		Estrogen-dependent gene expression NGF-stimulated transcription	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Heel bone mineral density ( 30598549 28869591)
Interacting Genes		6 interacting genes: DNMT3L EP300 JUN JUNB JUND SRA1	37 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595 ZSWIM9
Entrez ID		2354	3726
HPRD ID		01270	01303
Ensembl ID		ENSG00000125740	ENSG00000171223
Uniprot IDs		A0A024R0P6 K7EKC1 P53539	P17275 Q5U079
PDB IDs		5VPA 5VPB 5VPC 5VPD 5VPE 5VPF
Enriched GO Terms of Interacting Partners?
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