TARDBP and NACC1

Number of citations of the paper that reports this interaction (PubMedID 23022214)
1

Data Source:
BioGRID (pull down, pull down)

		TARDBP	NACC1
Description		TAR DNA binding protein	nucleus accumbens associated 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Perichromatin Fibrils Cytoplasmic Stress Granule Nuclear Speck Interchromatin Granule Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Sequence-specific DNA Binding Pre-mRNA Intronic Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II MRNA Processing RNA Splicing Negative Regulation Of Gene Expression Regulation Of Protein Stability Positive Regulation Of Insulin Secretion Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Import Into Nucleus Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Negative Regulation By Host Of Viral Transcription Rhythmic Process Regulation Of RNA Metabolic Process Regulation Of Cell Cycle 3'-UTR-mediated MRNA Destabilization 3'-UTR-mediated MRNA Stabilization Nuclear Inner Membrane Organization	Positive Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Beard thickness ( 26926045) Ewing sarcoma ( 22327514) Male-pattern baldness ( 22693459 28196072)	Obesity-related traits ( 23251661)
Interacting Genes		17 interacting genes: APP EXOSC10 FBXO7 FUS IRAK2 LSM6 MED6 NACC1 NSFL1C RACK1 RBM45 RNF2 SETDB1 UBQLN1 XRN2 ZFAND2B ZHX1	8 interacting genes: BCOR HDAC3 HDAC4 PML SENP1 SENP2 TARDBP UBE2I
Entrez ID		23435	112939
HPRD ID		05466	10692
Ensembl ID		ENSG00000120948	ENSG00000160877
Uniprot IDs		A0A024R4E2 Q13148 Q9H256	A0A024R7E0 Q96RE7
PDB IDs		1WF0 2CQG 2N2C 2N3X 2N4G 2N4H 2N4P 4BS2 4IUF 4Y00 4Y0F 5MDI 5MRG 5W50 5W52 5W7V 5WHN 5WHP 5WIA 5WIQ 5WKB 5WKD 5X4F 6B1G 6CF4 6CFH 6N37 6N3A 6N3B 6N3C	3GA1 4U2N
Enriched GO Terms of Interacting Partners?
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