ECPAS and MYH10

Number of citations of the paper that reports this interaction (PubMedID 20682791)
33

Data Source:
BioGRID (two hybrid)

		ECPAS	MYH10
Description		Ecm29 proteasome adaptor and scaffold	myosin heavy chain 10
Image		No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle	Stress Fiber Nucleus Cytoplasm Spindle Cytosol Polysome Brush Border Cell Cortex Myosin Complex Myosin II Complex Lamellipodium Growth Cone Midbody Neuromuscular Junction Cleavage Furrow Actomyosin Neuronal Cell Body Dendritic Spine Extracellular Exosome Myosin II Filament Glutamatergic Synapse
	Molecular Function	Protein Binding Molecular Adaptor Activity Proteasome Binding	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding ATPase Activity Actin-dependent ATPase Activity RNA Stem-loop Binding ADP Binding MRNA 5'-UTR Binding Actin Filament Binding
	Biological Process	Ubiquitin-dependent ERAD Pathway Proteasome Assembly	Mitotic Cytokinesis In Utero Embryonic Development Neuron Migration Plasma Membrane Repair Cardiac Septum Development Exocytosis Substrate-dependent Cell Migration, Cell Extension Nuclear Migration Cell Adhesion Axon Guidance Adult Heart Development Cell Proliferation Regulation Of Cell Shape Fourth Ventricle Development Lateral Ventricle Development Third Ventricle Development Cerebellar Purkinje Cell Layer Development Actin Filament-based Movement Actomyosin Structure Organization Aorta Development Positive Regulation Of Protein Secretion Neuromuscular Process Controlling Balance Cardiac Myofibril Assembly Ventricular Cardiac Muscle Cell Development Retina Development In Camera-type Eye Coronary Vasculature Development Modification Of Postsynaptic Actin Cytoskeleton Postsynaptic Actin Cytoskeleton Organization
Pathways			EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS			Type 2 diabetes ( 30130595)
Interacting Genes		30 interacting genes: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSPB1 MKI67 MYH10 PCM1 PCYT1B PSMC3 RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483	10 interacting genes: APC BCAP31 ECPAS MYH9 PBX1 PTEN S100A4 YWHAE YWHAG ZNF512B
Entrez ID		23392	4628
HPRD ID		11078	01178
Ensembl ID		ENSG00000136813	ENSG00000133026
Uniprot IDs			G1UI33 P35580
PDB IDs			4PD3
Enriched GO Terms of Interacting Partners?
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