MYH10 and PBX1

Number of citations of the paper that reports this interaction (PubMedID 12724421)
15

Data Source:
HPRD (two hybrid, in vivo)

		MYH10	PBX1
Description		myosin heavy chain 10	PBX homeobox 1
Image
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Spindle Cytosol Polysome Brush Border Cell Cortex Myosin Complex Myosin II Complex Lamellipodium Growth Cone Midbody Neuromuscular Junction Cleavage Furrow Actomyosin Neuronal Cell Body Dendritic Spine Extracellular Exosome Myosin II Filament Glutamatergic Synapse	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding ATPase Activity Actin-dependent ATPase Activity RNA Stem-loop Binding ADP Binding MRNA 5'-UTR Binding Actin Filament Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Mitotic Cytokinesis In Utero Embryonic Development Neuron Migration Plasma Membrane Repair Cardiac Septum Development Exocytosis Substrate-dependent Cell Migration, Cell Extension Nuclear Migration Cell Adhesion Axon Guidance Adult Heart Development Cell Proliferation Regulation Of Cell Shape Fourth Ventricle Development Lateral Ventricle Development Third Ventricle Development Cerebellar Purkinje Cell Layer Development Actin Filament-based Movement Actomyosin Structure Organization Aorta Development Positive Regulation Of Protein Secretion Neuromuscular Process Controlling Balance Cardiac Myofibril Assembly Ventricular Cardiac Muscle Cell Development Retina Development In Camera-type Eye Coronary Vasculature Development Modification Of Postsynaptic Actin Cytoskeleton Postsynaptic Actin Cytoskeleton Organization	Branching Involved In Ureteric Bud Morphogenesis Steroid Biosynthetic Process Positive Regulation Of Transcription Of Notch Receptor Target Sex Differentiation Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Ossification Adrenal Gland Development Embryonic Limb Morphogenesis Somatic Stem Cell Population Maintenance Embryonic Hemopoiesis Negative Regulation Of Neuron Differentiation Spleen Development Thymus Development Embryonic Skeletal System Development
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs	Transcriptional regulation of pluripotent stem cells Activation of anterior HOX genes in hindbrain development during early embryogenesis NOTCH3 Intracellular Domain Regulates Transcription
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
GWAS		Type 2 diabetes ( 30130595)	Asthma ( 29273806) Breast cancer (prognosis) ( 23319801) Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903) Early-onset Parkinson's disease ( 28256260) Height ( 20966902) Myopia ( 27182965) Night sleep phenotypes ( 27126917) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		10 interacting genes: APC BCAP31 ECPAS MYH9 PBX1 PTEN S100A4 YWHAE YWHAG ZNF512B	23 interacting genes: CREBBP HOXA10 HOXA5 HOXA9 HOXB1 HOXB7 HOXB8 HOXD10 HOXD4 HOXD9 KAT2A MDM2 MEIS1 MEIS2 MYH10 NEDD4L NR3C1 PAX6 PBX2 PDX1 PKNOX1 POU2F1 SMARCD3
Entrez ID		4628	5087
HPRD ID		01178	08889
Ensembl ID		ENSG00000133026	ENSG00000185630
Uniprot IDs		G1UI33 P35580	A1MJ41 A8K5V0 P40424 Q53YC7
PDB IDs		4PD3	1B72 1PUF
Enriched GO Terms of Interacting Partners?
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