SYNE1 and ECPAS

Number of citations of the paper that reports this interaction (PubMedID 20682791)
33

Data Source:
BioGRID (two hybrid)

		SYNE1	ECPAS
Description		spectrin repeat containing nuclear envelope protein 1	Ecm29 proteasome adaptor and scaffold
Image			No pdb structure
GO Annotations	Cellular Component	P-body Cell Nucleus Nuclear Envelope Nuclear Outer Membrane Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytoskeleton Integral Component Of Membrane Sarcomere Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Postsynaptic Membrane	Proteasome Complex Nucleus Nucleoplasm Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	RNA Binding Actin Binding Protein Binding Lamin Binding Enzyme Binding Protein Homodimerization Activity Actin Filament Binding	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	Nucleus Organization Golgi Organization Spermatogenesis Muscle Cell Differentiation Cytoskeletal Anchoring At Nuclear Membrane Nuclear Matrix Anchoring At Nuclear Membrane	Ubiquitin-dependent ERAD Pathway Proteasome Assembly
Pathways		Meiotic synapsis
Drugs
Diseases		Emery-Dreifuss muscular dystrophy Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 28115744 21926972 31043756 28072414 20351715 21738484) Bipolar disorder or major depressive disorder ( 20351715) Bipolar I disorder ( 31043756) Body mass index ( 26426971) Endometriosis ( 28537267) Heel bone mineral density ( 30598549 28869591) Post bronchodilator FEV1 ( 26634245) Tonometry ( 17903302) Uterine fibroids ( 31249589 30194396 31649266)
Interacting Genes		18 interacting genes: ACTC1 APC CAPN1 CDC42 CDC5L CEP63 DISC1 DTNBP1 ECPAS EMD LINC00839 LMNA MTDH MUSK NDEL1 SH3BP5 TNIK USP21	30 interacting genes: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSPB1 MKI67 MYH10 PCM1 PCYT1B PSMC3 RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		23345	23392
HPRD ID		09762	11078
Ensembl ID		ENSG00000131018	ENSG00000136813
Uniprot IDs		A0A0C4DG40 B4E3R1 B7Z9Y6 F8WAI0 Q8NF91
PDB IDs		4DXR
Enriched GO Terms of Interacting Partners?
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