JADE2 and SASH1

Number of citations of the paper that reports this interaction (PubMedID 30480076)
2

Data Source:
BioGRID (two hybrid)

		JADE2	SASH1
Description		jade family PHD finger 2	SAM and SH3 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome	Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding Transferase Activity Metal Ion Binding	G-protein Alpha-subunit Binding Protein Binding Protein C-terminus Binding Protein Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Molecular Adaptor Activity
	Biological Process	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Protein Polyubiquitination Positive Regulation Of Endothelial Cell Migration Regulation Of Epithelial Cell Migration Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of JUN Kinase Activity Positive Regulation Of Angiogenesis Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of P38MAPK Cascade Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Protein Autoubiquitination
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Body mass index ( 28892062) Coffee consumption ( 31046077) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244) Platelet distribution width ( 27863252) Type 2 diabetes ( 28869590)	Alzheimer's disease ( 20061627) Chronotype ( 30696823) Gait speed in old age ( 28077804) Hypothyroidism ( 27182965) Idiopathic dilated cardiomyopathy ( 29495422) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Pneumococcal meningitis x streptococcus pneumoniae antigen allele interaction ( 31092817) Protein quantitative trait loci ( 18464913) Resting-state electroencephalogram vigilance ( 29703947) Rotator cuff tears ( 26350878) Thyroid hormone levels ( 23408906) Type 2 diabetes nephropathy ( 21150874)
Interacting Genes		9 interacting genes: FBXO7 GORASP2 H3-4 ING5 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF496	26 interacting genes: AFF1 AKAP10 ARRB1 ASCC2 C1D CCNDBP1 CNKSR1 CRK CRKL CTNNA1 EPS8L2 EXOC8 IKBKB JADE2 JADE3 KHDRBS1 KIF3B PPP4R1 RBM12B SECISBP2L SKIL SNX1 SPG7 SYNE2 TNKS2 UTRN
Entrez ID		23338	23328
HPRD ID		15124	06408
Ensembl ID		ENSG00000043143	ENSG00000111961
Uniprot IDs		A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1	O94885
PDB IDs			2DL0 2EBP
Enriched GO Terms of Interacting Partners?
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