SCFD1 and DLST

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SCFD1	DLST
Description		sec1 family domain containing 1	dihydrolipoamide S-succinyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi-associated Vesicle Cis-Golgi Network Cytosol Plasma Membrane Golgi Cisterna Membrane	Nucleus Mitochondrion Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex
	Molecular Function	Protein Binding Syntaxin Binding Protein-containing Complex Binding Protein N-terminus Binding	Dihydrolipoyllysine-residue Succinyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Cell Morphogenesis Response To Hypoxia Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Vesicle Docking Involved In Exocytosis Response To Toxic Substance Protein Transport COPII Vesicle Coating Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Toxin Transport Negative Regulation Of Autophagosome Assembly	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Succinylation
Pathways		COPII-mediated vesicle transport	Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 29566793 27455348) Cognitive decline (age-related) ( 28078323) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mood instability ( 29187730) Non-small cell lung cancer ( 23144319)
Interacting Genes		6 interacting genes: DLST HECTD1 PPBP STX5 USO1 USP22	15 interacting genes: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1
Entrez ID		23256	1743
HPRD ID		10210	00520
Ensembl ID		ENSG00000092108	ENSG00000119689
Uniprot IDs		B7Z5N7 B7Z738 Q8WVM8	A0A024R6C9 B7Z6J1 P36957
PDB IDs
Enriched GO Terms of Interacting Partners?
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