SYT11 and SYNCRIP

Number of citations of the paper that reports this interaction (PubMedID 10734137)
26

Data Source:
HPRD (in vitro)

		SYT11	SYNCRIP
Description		synaptotagmin 11	synaptotagmin binding cytoplasmic RNA interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Cell Lysosome Lysosomal Membrane Trans-Golgi Network Plasma Membrane Synaptic Vesicle Postsynaptic Density Cell Junction Axon Dendrite Clathrin-coated Vesicle Membrane Vesicle Early Phagosome Neuron Projection Terminal Bouton Dendritic Spine Perikaryon Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Recycling Endosome Recycling Endosome Membrane Excitatory Synapse Inhibitory Synapse Exocytic Vesicle Schaffer Collateral - CA1 Synapse Presynapse Integral Component Of Presynaptic Active Zone Membrane	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex Ribonucleoprotein Complex
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Clathrin Binding Translation Initiation Factor Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Beta-tubulin Binding	RNA Binding MRNA Binding Protein Binding Poly(A) Binding MRNA 5'-UTR Binding
	Biological Process	Plasma Membrane Repair Vesicle Fusion Autophagy Learning Memory Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Dopamine Secretion Negative Regulation Of Endocytosis Negative Regulation Of Neurotransmitter Secretion Negative Regulation Of Cytokine Secretion Negative Regulation Of Phagocytosis Establishment Of Vesicle Localization Cellular Response To Calcium Ion Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Synaptic Vesicle Endocytosis Regulation Of Defense Response To Bacterium Negative Regulation Of Microglial Cell Activation Negative Regulation Of Tumor Necrosis Factor Secretion Negative Regulation Of Membrane Invagination Regulation Of Phagosome Maturation Positive Regulation Of Protein Localization To Phagocytic Vesicle Negative Regulation Of Clathrin-coated Pit Assembly Calcium Ion Regulated Lysosome Exocytosis	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Parkinson's disease ( 21292315 25064009) Serum cancer antigen 15.3 levels ( 31666285)
Interacting Genes		4 interacting genes: APPBP2 PRKN SGTA SYNCRIP	31 interacting genes: A1CF APOBEC1 APP CSDE1 EPRS1 ESR1 GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9
Entrez ID		23208	10492
HPRD ID		12289	06734
Ensembl ID		ENSG00000132718	ENSG00000135316
Uniprot IDs		Q9BT88	B7Z645 O60506 Q59GL1
PDB IDs			2DGU 2MXT 2NBB
Enriched GO Terms of Interacting Partners?
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